What is Pramipexole? Using it in bodybuilding

Pramipexole is a dopamine agonist and belongs to the same class of drugs as Cabergoline. The main purpose of this drug is to treat Parkinson's disease. Apo Pramipexole is most commonly found under the brand names Sifrol, Mirapexin and Mirapex, and generics are also available.

Mirapex is the most famous brand of the pharmaceutical company Boehringer Ingelheim Pharmaceuticals. Along with the treatment of Parkinson's disease, Pramipexole is used to treat restless legs syndrome. Also, the drug has shown effectiveness in the treatment of bipolar disorder, although it was not officially created for these purposes.

Functions and properties of Pramipexole

Pramipexole is a dopamine agonist that is directly related to the hormone prolactin. When dopamine levels rise in the body, prolactin levels drop. The drug has a direct effect on the dopamine D3 receptor. Although it also acts on the D2 receptor, its affinity for the D3 receptor is seven times stronger than that of any dopamine agonist in existence.

The action of Pramipexole on the D3 receptor has a strong effect on the nervous system, which is why it is used to treat Parkinson's disease, and in some cases, Alzheimer's disease. Acting on the D3 receptor, Pramipexole also affects sexual desire and activity in men.

Prolactin is partially responsible for a man's refractory period, which refers to the recovery time from sexual activity in order to increase productivity again. By lowering prolactin and increasing dopamine, Pramipexole can directly reduce the refractory period, which leads to the ability to perform sexual function more often.

Action of Pramipexole

The medical benefits of Apo Pramipexole are manifested in the relief of symptoms of Parkinson's disease and in improving the mood of patients. However, the drug is used by athletes to improve performance, primarily to combat a specific type of gynecomastia and improve sexual function, which is often diminished with certain anabolic steroids.

When prolactin levels rise significantly, along with rising estrogen levels, it can lead to gynecomastia (enlarged male breasts). Even by controlling estrogen, gynecomastia can still occur in men who are sensitive to Gynecomastia. The increase in prolactin levels during steroid use is most commonly associated with the hormones Nandrolone (Deca Durabolin) and Trenbolone.

Not all men will have problems with an increase in prolactin while taking these steroids, as this depends on dosage and genetic predisposition. If control is needed, then Pramipexole is ideal for control. Elevated levels of prolactin also have a negative effect on a man's sexual activity, mainly in the inability to achieve and maintain an erection.

The most well-known steroid that leads to this condition is Nandrolone, the hormone responsible for the phrase "Deca-dick". Those who have problems with erection often refuse Nandrolone, which is fully explained by its effect on potency.

However, in most cases, low doses of Pramipexole can offset these problems. In fact, the right combination of steroid hormones when combined with Pramipexole can help you achieve peak sexual performance.

The last positive effect of Apo Pramipexole is to increase the production of growth hormone (GH). The increase in production, although not significant, is sufficient reason for an increase in serum GH levels approximately two hours after taking the drug.

Side effects of Pramipexole

There are several possible side effects of Apo Pramipexole, probably more than most dopamine agonists. Side effects of Pramipexole depend on genetic predisposition, some may not show them at all, while some may be very annoying. Possible side effects of Pramipexole include:

• Nausea (most common side effect)

• Vomiting

• Loss of appetite

• Headaches

• Swelling (mainly in the legs, ankles and / or feet)

• Insomnia and dizziness (fainting is possible, but not often)

• Hallucinations (rare)

• Muscle cramps

• General weakness

The most common cause of the above side effects is drug abuse. Pramipexole is a powerful drug and should not be abused. The dosage of this dopamine agonist should always be kept to a minimum.

Pramipexole Review

Apo Pramipexole is the strongest dopamine agonist on the market and its ability to improve sexual function is amazing. However, from a medical point of view, the drug is not often prescribed for these purposes, but there is practically no data on why this is so.

While potent, it is also one of the strongest dopamine agonists in terms of controlling side effects, especially when it comes to indigestion. For many, Cabergoline may be the best option, which is easier to control, but Pramipexole is the most acceptable option.